TOXOPLASMOSIS OF THE CENTRAL NERVOUS SYSTEM IN HIV PATIENTS

Abstract

Currently HIV infection in Kazakhstan is mainly spread among population groups with risk taking behavior (injection drug users - IDUs, sex workers - SWs). The lesions and fatalities in patients with HIV infection are mainly caused by complications, i.e. the development of opportunistic infections and secondary diseases. Timely diagnosis of these conditions determines the success of treatment and life expectancy of patients. Among superinfections the following ones take the lead: mycoses (pneumocystosis, candidiasis, cryptococcosis, coccidioidosis), diseases caused by a group of herpes viruses (herpes simplex, herpes zoster, cytomegalovirus infection, Epstein-Barr virus infection, Kaposi's sarcoma), bacterial infection (tuberculosis, atypical mycobacteriosis, salmonellosis), protozoosis (toxoplasmosis, cryptosporidiosis). Multi-infections are common as well. Opportunistic infections are insidious in humans and take the form of endogenous infections; they as well are activated with the development of clinical manifestations along with formation of immunodeficiency and, accordingly, cause severe and even fatal diseases.