CLINICAL CHARACTERISTICS OF PATIENTS WITH COVID-19

Authors

  • A.R Obloqulov Bukhara State medical institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
  • G.E Niyozov Bukhara State medical institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
  • A.A. Elmurodova Bukhara State medical institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
  • D.U. Orifov Bukhara State medical institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan

DOI:

https://doi.org/10.26577/IAM.2020.v1.i2.06

Keywords:

COVID-19, coagulation, prothrombin time, D-dimer, C-reactive protein, procalcitonin, ferritin

Abstract

A new virus, called acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread all over the world, became a pandemic one. Inspite of that clinical profile of patients has been reported, there is a lack of information regarding the presentation of patients with COVID-19 requiring emergency care and in particular about those who emergency medical services. We described the main clinical characteristics of patients with Covid-19. It’s a single-center retrospective cohort study. All COVID-19 patients included in this study were diagnosed according to the guidelines for the diagnosis and treatment of pneumonia caused by infection with the novel coronavirus. All patients had laboratory-confirmed infection with SARS-CoV-2 (real-time RT-PCR specific for SARS-CoV-2 was positive).The value of Ddimer coagulation indices, prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen as well as C-reactive protein, procalcitonin, ferritin in predicting the severity and prognosis of COVID-19 was studied. Dysfunction of blood coagulation and procalcitonin are widely used to assess the risk of bacterial infection and C-reactive protein - an indicator of an acute inflammatory process - was found in almost everyone, more often in severe patients.

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Published

2020-12-20