REACTIVATION OF BRUCELLOSIS AND RHEUMATOID ARTHRITIS IN PREGNANCY

Abstract

Brucellosis is a zoonotic infectious-allergic disease caused by bacteria of the genus Brucella, mainly characterized by damage of the musculoskeletal, nervous, genitourinary, and other organ and systems. In women, brucellosis results in miscarriage, primary or secondary infertility. But little is known about the course of pregnancy with a combination of brucellosis and autoimmune pathology such as rheumatoid arthritis. Report the course and outcome of brucellosis and rheumatoid arthritis in pregnancy.  We analyzed a clinical case of a pregnant woman with chronic brucellosis and rheumatoid arthritis. In a patient with chronic brucellosis in the first trimester of pregnancy, brucellosis intensified with the development of acute monoarthritis. Arthritis regressed after a course of antibiotic therapy in the second trimester, but there was an activation of rheumatoid arthritis and preterm labor in the third trimester.This case showed a more severe course of brucellosis during pregnancy compared with rheumatoid arthritis and the importance of antibiotic therapy to prevent severe complications.